March 13, 200817 yr http://www.youtube.com/watch?v=B2OAr4YSfbY "They've gone up 50 levels in three weeks" "My God they must have no lives at all" Me and my other room mate were watching this episode the other day and he pointed out Pete got to level 70 in three weeks.
March 13, 200817 yr 30,000 people a year wake during surgery New monitors no help for patients 'entombed in a corpse,' study says The Associated Press updated 5:00 p.m. ET, Wed., March. 12, 2008 ... Some remember hearing their surgeons talk, ... Last October I was under general anesthesia for 14 hours for cancer surgery and reconstructive surgery. The following week in ICU, with abundant pain meds, was such a strange and disorienting experience that I'm not sure what I really experienced and what I hallucinated, but I have a memory of hearing doctors talking about real estate/condo development that may have been during surgery. I don't remember any pain or fear, though. I guess I should ask my doctor if what I think I remember is real. I'm pretty sure she'd level with me if it was.
March 13, 200817 yr Yeah that is a great movie. Also, if you haven't seen "Dogville", rent it. Incredible, especially the moral to the story.
March 13, 200817 yr "They've gone up 50 levels in three weeks" "My God they must have no lives at all" Me and my other room mate were watching this episode the other day and he pointed out Pete got to level 70 in three weeks. His parents must be so very, very proud.
March 13, 200817 yr Yeah that is a great movie. Also, if you haven't seen "Dogville", rent it. Incredible, especially the moral to the story. I think I would have to prepare myself emotionally for that one. I hear it's dreary. With a capital dreary.
March 13, 200817 yr ^Yeah, it's hard to watch at times. It really makes you think about arrogance in a whole new light though.
March 14, 200817 yr Client 9, it the new fragrance from CK LMAO!! LMAO!! I bet people are booking the mayflower hotel like nobody's business. i saw something about that today: 3/13 | 2:15 PM Checking In at the Mayflower Hotel Looks like D.C. has another infamous hotel. The city appears tickled with its role in the Spitzer scandal: Cameras and secret-service vans have been inexplicably parked outside the entrance to the Mayflower Hotel (the site of the governor's infamous tryst with "Kristen") since the news broke Monday (he's not there now, people). But what's happening inside? For one, there haven't been many requests for the "Spitzer suite," said the petrified concierge, who turned white as a ghost when we asked about "the room." A security guard has been stationed outside room 871, but that hasn't stopped guests from taking a look. "It looks just like any other room," said Mary Hollebeck, in from Michigan for the National Funeral Directors conference. She and her husband, Martin, found out about the scandal after they'd checked in, and said the guests in the hotel have been enjoying the buzz. "Right now I'm sure the hotel probably wants it all just to go away," he said. "But then they'll probably go and raise the rate." So do they find the rooms romantic? "We usually come on business," Mary said, to which Martin interjected, "I want this to be clear: This is my wife." —
March 14, 200817 yr "So do they find the rooms romantic? "We usually come on business," Mary said, to which Martin interjected, "I want this to be clear: This is my wife." —" Ha ha ... nice!
March 15, 200817 yr Ok.. I might be late on this, but I think I caught the DragonForce bug.. :banger:
March 15, 200817 yr Ahh yes! Pac-Man! The game of all games. The great thing about Pac-Man was you could play forever on one quarter if you knew the pattern LOL. Never played Super Pac-Man though.
March 15, 200817 yr Ok.. I might be late on this, but I think I caught the DragonForce bug.. :banger: What's this Dragon Force Bug you speak of?
March 15, 200817 yr ^^they are that power metal band from england.. their really popular song is the hardest song on guitar hero http://www.dragonforce.com/main.html
March 15, 200817 yr I've planned several meetings at the Mayflower and have kept in touch with a couple of people there. They are NOT enjoying this type of media attention and have now taken "the room" completely out of the reservations system until the press dies down. And on an unrelated side note, I'm back. I know you were all on the edge of your seats.
March 15, 200817 yr I went out for a conference so that's pretty much where I spent my last two days, but I did get a lot of fun things in beforehand. I went to the beach like 3 times. It's nice to go now because in LA it's not beach weather yet (yeah, only 70) so there weren't very many people there. I picked up stuff from the grocery and made little picnic lunches there and read books, walked along the water, it was amazing. I hung out in Topanga quite a bit, it's my favorite area of LA. It's kind of like where all the old hippies live, only now they all have corporate jobs and their lean-to shacks have been built up and are now worth millions. But it retains its hippies and it's funky, informal vibe and it's a great place to hang. It also gets more sun so it was warmer there. I had slow, leisurely breakfasts 3 different mornings at Pat's (google it if you want, pat's topanga grill) on the porch in the sun, eating oatmeal and fruit and working on my book. I finished an entire chapter while I was there and got a pretty good start into another, which is nice. I did a little shopping in Santa Monica and got some cool stuff on sale at the Lucky store, a new Product (RED) shirt on sale at the Gap and sat at an outdoor cafe eating a cheese and fruit plate with olives and bordeaux. Life could be worse. Thursday night of the conference I took my 2 co-workers and a girl I befriended out for the night instead of going to the conference dinner "bash," which usually isn't very good. We went to El Coyote, which is a wonderful, loud, cheap mexican place in west hollywood (for you trivia hounds, it's where Sharon Tate ate her last meal). I drove everyone up into my neighborhood where I used to live before dinner and we marveled at the mansions and beautiful landscaping. It's amazing I used to live there. After dinner we went to Barney's Beanery and when we valeted the car there was some to-do going on a few doors down. I though it was nothing til I saw the E! truck so then we went walking over to see what was up. It was the wrap party for the show 'How I Met Your Mother,' which I don't watch so I don't know who most of the people are that were there but I did recognize Bob Saget and Neil Patrick Harris. They were giving press interviews and pix were being taken. I was so happy I got my friends a "star" sighting on our only night out. So shopping, hanging out on the beach, eating great food and getting some sun. Could be worse.
March 15, 200817 yr "So shopping, hanging out on the beach, eating great food and getting some sun. Could be worse." You lucky b!tch poor thing - welcome back! :-) clevelandskyscrapers.com Cleveland Skyscrapers on Instagram
March 15, 200817 yr Sounds like a great time. What kind of book are you writing, fiction? Traveling should have given you some inspiration.
March 15, 200817 yr "So shopping, hanging out on the beach, eating great food and getting some sun. Could be worse." You lucky b!tch poor thing - welcome back! :-) LOLZ.
March 15, 200817 yr Sounds like a great time. What kind of book are you writing, fiction? Traveling should have given you some inspiration. Actually non-fiction, my autobiography. I've had too many people tell me I should write a book upon hearing some of my life stories so that's what I'm doing, have been working on it for some time. I will have to consult with lawyers on how to edit it so I won't get sued, maybe even publish under a fake name or something.
March 16, 200817 yr Remember it's not defamation if it's the truth! Let 'em have it :whip: I've thought of that, but without getting too esoterical, isn't truth how you define it? Maybe you or I would both describe someone as a controlling, psychopathic jerk but they don't think of themselves that way, and defaming them could, in theory, harm their careers, so there's your lawsuit. Do you have a good defense? Sure, but who can afford that kind of problem.
March 16, 200817 yr The difference between belief and truth is that truth is somehow verified. It would be extremely hard for someone to prove that your statements are false, especially if they're vague. If you call someone a psychopath, they would have to go to a psychologist and prove that they don't have anti-social personality disorder (and maybe expose their criminal record, as anti-social personality disorder correlates to deviant behavior, usually crime and amoral behavior) but if you said "so and so had the eyes of a psychopath" or "so and so had psychopathic tendencies as exemplified by blah blah blah" then I don't see how they could prove defamation. Also, you cannot lose in a defamation suit if it's clear that you're giving your own personal opinion. Think about all the lawyers like Ann Coulter and Bill Cunningham in the media that say ridiculous things that seem like they would warrant a defamation of character suit. It's crazy what people get away with. Seems like it happens in hollywood entertainment a lot because they say blatantly false things (as it sells many copies, to make up for it). I'm definitely not a lawyer though, law is really fascinating to me.
March 16, 200817 yr The difference between belief and truth is that truth is somehow verified. It would be extremely hard for someone to prove that your statements are false, especially if they're vague. If you call someone a psychopath, they would have to go to a psychologist and prove that they don't have anti-social personality disorder (and maybe expose their criminal record, as anti-social personality disorder correlates to deviant behavior, usually crime and amoral behavior) but if you said "so and so had the eyes of a psychopath" or "so and so had psychopathic tendencies as exemplified by blah blah blah" then I don't see how they could prove defamation. Also, you cannot lose in a defamation suit if it's clear that you're giving your own personal opinion. Think about all the lawyers like Ann Coulter and Bill Cunningham in the media that say ridiculous things that seem like they would warrant a defamation of character suit. It's crazy what people get away with. Seems like it happens in hollywood entertainment a lot because they say blatantly false things (as it sells many copies, to make up for it). I'm definitely not a lawyer though, law is really fascinating to me. Yes, but there are different rules that apply to people who are "well known" or in the public eye vs. private citizens and defamation so whatever you hear on TV is not the same thing. Believe me, I've researched it. I'm just not sure how I can say the things I have to say without getting sued. I'm confident I would WIN if things did go to court, but I don't have the money for that kind of legal troubles. Being on the correct legal grounds doesn't prevent someone from suing you.
March 16, 200817 yr I have this crazy tendency to not recognize people I know, in public. I don't understand it. Either my long term memory is shot or I need glasses, I don't know, but it makes for some pretty awkward situations when people approach me. Anyone else have this problem with facial recognition? This is becoming a serious problem lol
March 16, 200817 yr I have this crazy tendency to not recognize people I know, in public. I don't understand it. Either my long term memory is shot or I need glasses, I don't know, but it makes for some pretty awkward situations when people approach me. Anyone else have this problem with facial recognition? This is becoming a serious problem lol It happens to me a lot, and has for years. If it's any consolation, it doesn't seem to progress as I get older. Yeah, it's embarrassing sometimes because I've met so many people in so many places over the years, that I often run into people I've met before at public events, and I have to fake the conversation for a little bit until I figure out who they are. Some people are actually offended that I don't put the name with the face right away. I don't understand why it is, especially compared with some other people, who can pick me out of a crowd even when we haven't seen each other in years. A few years ago on a train, a guy came right up to me and called me by name; I hadn't a clue as to who he was. Turned out to be a guy who had gone to high school with my two-years-younger brother, and we hadn't seen each other since high school. Trust me, I don't look much like I did fifty years ago. I don't always blame myself, though. Among my pool of acquaintances are quite a few middle-aged-to-older, overweight guys with graying hair and full beards, and they look so much alike that if you were to put them in a police lineup, it would be hard to tell one from another. I have to spend enough time around them to lock in on various mannerisms and speech patterns before I can recognize them later on.
March 16, 200817 yr I have this crazy tendency to not recognize people I know, in public. I don't understand it. Either my long term memory is shot or I need glasses, I don't know, but it makes for some pretty awkward situations when people approach me. Anyone else have this problem with facial recognition? This is becoming a serious problem lol Lay off the weed, bro. http://www.gardenscure.com/420/marijuana-cooking/52152-marijuana-capsules.html
March 16, 200817 yr It happens to me a lot, and has for years. If it's any consolation, it doesn't seem to progress as I get older. Yeah, it's embarrassing sometimes because I've met so many people in so many places over the years, that I often run into people I've met before at public events, and I have to fake the conversation for a little bit until I figure out who they are. Some people are actually offended that I don't put the name with the face right away. I don't understand why it is, especially compared with some other people, who can pick me out of a crowd even when we haven't seen each other in years. A few years ago on a train, a guy came right up to me and called me by name; I hadn't a clue as to who he was. Turned out to be a guy who had gone to high school with my two-years-younger brother, and we hadn't seen each other since high school. Trust me, I don't look much like I did fifty years ago. I don't always blame myself, though. Among my pool of acquaintances are quite a few middle-aged-to-older, overweight guys with graying hair and full beards, and they look so much alike that if you were to put them in a police lineup, it would be hard to tell one from another. I have to spend enough time around them to lock in on various mannerisms and speech patterns before I can recognize them later on. Rob, this happens to me too. I usually ask someone in my office to stand to the left or right of me at a meeting or event so they can whisper who is approaching. When I was in DC last month, at the airport this guy, spoke to me by name and thanked me for inviting him to our luxury event. He even inquired about my mother, my best friend, and another friend - I had no clue who he was. All I could do to quickly recover was say, "that's kind, I'm so happy that you both enjoyed yourselves. Please let me have your card so I can make sure you are advised of any future events similar in nature" As soon as I got into the motorized coach I called my assistant and asked who that person is - he was like, "You, idiot" that what the Queen of Jordan's press secretary.
March 16, 200817 yr ...I usually ask someone in my office to stand to the left or right of me at a meeting or event so they can whisper who is approaching...
March 16, 200817 yr I'm leaving out the email addresses to keep their identities secret, but on the still-thriving email list from my band that played its last gig in 2001, the conversation occasionally deviates from beer, drunken anecdotes, Black Sabbath, what-might-have-been, upcoming weddings, upcoming divorces, to this kind of stuff. This is a back-and-forth between the bass player and the sax player's girlfriend: I was never unconvinced that you understood genomics (and your knowledge of it is more extensive than I thought), though you're still looking at it from the perspective of a geneticist - and revealed as much when you claimed that we're in the "post-genomic era" in your last email. I'm too hung-over to go into the detail you did, but suffice it to say that the "theory" which you appallingly called not "important" is still very much important and is still in the process of development. The fact that you were manually aligning genes because Clustal didn't work for you, or talking about how the statistics for tiling arrays hasn't been worked out well for bacteria, should've proved that. But I will agree that people in genomics tend to have less understanding of biology than they should, however I am not one of those people; I've worked in a molecular biology (yeast!) lab and am currently collaborating with a microbiology lab, and my medical training is quite a bit broader than what I would've learned in a classic bioinformatics PhD. I think that in general bioinformaticists know a little about a lot of different fields (biology, chemistry, physics, math, and computer programming/ engineering) , and basic scientists know a lot about one or a few fields, which makes communication between them so vital. If we want to get nasty about whose work or knowledge is more "important," I would have to point out that you said absolutely nothing about human genomics, only to imply they're not interesting because you can't know as much about the whole organism as you can in micro-organisms. But as an MD, I can see where genomics is headed in both clinical diagnosis and treatment. Both pharmacogenomics and cancer genomics will play a vital role in identifying gene profiles that will change the course of treatment, for example. Although it would be nice to know what all those genes do at a molecular level (and those processes will be examined by geneticists in the future), it means squat to a patient with terminal lung cancer, who would be more interested in knowing why their chemo is not succeeding. Sorry for wallowing in my usual rhetorical style. I know you didn't mean to imply that my work is not important, but I wanted to make sure you knew that's what it sounds like. You see genomics only as a tool to send genetics in the right direction, but forget that it is doing important work in and of itself, right now and in the future. I'm hoping when you said "post-genomic" you meant "post-sequencing. " HMMs have been used on DNA in the past, and I think they still are (or they ought to be), though they are much better applied to proteins, as you said. This is considered to be one of the best introductions to biological sequence analysis; I certainly can attest to that, although someone stole my copy years ago!: http://www.amazon. com/Biological- Sequence- Analysis- Probabilistic- Proteins/ dp/0521629713/ ref=cm_lmf_ tit_1_rsrscs0 I can't suggest a program for RNA alignment off hand, though I could ask my advisor what he thinks. The reason I can't help much with packaged programs is that I avoid them, since I prefer to write the programs my damn self! That way, I have a much better understanding of what they're doing. (Of course, as the programs get more complicated, I'll have to abandon that sentiment due to the time constraint, but it is still vital to understand what the program actually does, so you know what to do when it doesn't do what you expected it to do.) Collaborating on tiling array analysis would be interesting, though it's far from what I'm doing right now. If you give me some background and tell me what exactly you're trying to get out of it, I might look into it during my down time - May and June. Thank you for the birthday wishes. This year it coincided with the St. Patrick's Day Parade, which is just an excuse for people to wear green and drink. So it worked out well for me! -Anonymous On Sat, 15 Mar 2008, Anonymous #2 wrote: > > . > > > True, Wash U is one of the top 3 sequencing centers, probably in the world. > They are producing something like 100 *tera*bits of information per day, I > believe! Its a major major problem facing, probably all fields, but > especially biology these days. So much information! Where to put it? How > to interpet it? > > Anyway, I didn't know you knew about HMM's (which is technically proteomics, > but hey; or can you use it effectively for DNA sequence? An aside: I am > being totally frustrated with RNA alignments-- there is just so much less to > work with in nucleic acids than protein. Only 4 bases (per type, 5 total of > course) and it is not clear at all what is a "conservative" change. Is T to > A (maintain base pairing) more conservative than T to C (maintain > pyrimidine)? Totally depends. I'm talking non-coding RNAs here, so > maintaining amino acid content is irrelevant.. . Do you know any good > programs other than typical Clustal? Especially for RNA covariance?) but > nonetheless, I maintain my claim. > > I know the practice, you know the theory. Genomics and proteomics are just > tools--I know how to think about that data and where to go from there to > prove something interesting. The time is long since past when you could do > just a microarray and publish it (as Monica knows well!), now it is just > another type of screen. The important thing is to understand what > microarray data means biologically and how to use that data. Otherwise it > is just useless information in an Excel spreadsheet. That's what I meant by > I know genomics as well, or better, than you. I don't know the statistics, > but I do know what is important! > > Plus, I've been to a pure Genomics conference and I work in micro-organisms > which means we not only had the first microarrays, but now have tiling > microarrays. That's one of the crucial advantages I love about single-cell > organisms: they are simple enough that you can understand them at a very > detailed level, including what ALL of their genes are and what ALL of their > proteins do. (Which isn't to say that we do yet: 25-50% of the genes in E. > coli (4000) and S. cerevisiae (6000) are still totally uncharacterized. But > it is much more feasible.) And micro-organisms are so abundant that you can > easily do comparisons across widely divergent species, which gives > substantial insight--as I'm sure I don' t need to tell the self-styled > genomicist! I witnessed the lab downstairs develop the first glass-slide > array for Bacillus (now pretty archaic), I observed the lab across the hall > develop new technology to assay yeast DNA replication on a genome-wide > scale, I rotated in a lab while they were working up a novel > chaperone-trapping proteomic screen. I've read countless papers and seen > endless talks using microarray technology and proteomics in extremely > diverse ways. Plus, at MIT, I was surrounded by engineering- y people doing > all kinds of genome-wide screens for transcription- factor binding sites > (ChIP-chip), alternative splicing sites (computational screens), non-coding > RNAs, the synthetic biology movement (resynthesizing the entire genome of > bacteria/yeast to have no TGA stop codons, for example, so you can insert a > TGA in your favorite gene to employ non-natural amino acids to add a > chemical crosslinker, etc), etc. Not to mention the Broad (which is kind of > a cesspool, I hear) and the other arm of the HGC, of course!! Oh, and of > course, then there is all the awesome directed evolution work going on now > in microbes, where they "evolve" a yeast or bacterial strain under various > conditions, eg limiting glucose for 500 generations in a chemostat, and then > sequence the WHOLE GENOME to find out what mutations they now have. And > then do biology on a genome-wide scale to find out what physiological > changes are going on (the oft-maligned metabolomics) . Super cool. If I had > gone to Wisconsin, that would've been my project with super-UV-resistant E. > coli. Oh, and the other postdoc I didn't do was at U Toronto (a HUGE HUGE > HUGE powerhouse of genomic/proteomic technology-- they are the ones who did > the first proteome-wide interaction studies, for example; they developed the > 386-well plate, etc.) basically doing the genomics of DNA repair in yeast. > I didn't go there specifically BECAUSE it was too genomic (and because it > was a weird situation being co-advised by THREE professors, two of whom were > brand-new to Toronto and who had start up money, while the guy I applied to > was in a funding crunch...)-- ultimately, I like to think at a more detailed, > mechanistic level. But it was way cool and I came awfully close to going > there... Plus, I got to see lots of cool biology robots when I > interviewed. .. > > I haven't yet done an array, though I am dying too, but I have done 2D gels > (proteomics) and a TON of protein alignments. That was my side-project in > grad school--manual alignments of my gene from every organism I could find > it in (including digging the sequence out of raw sequencing data for most > organisms, complete with tons of sequencing errors, which made it quite > tricky). And aligning my gene with all the other members of the polymerase > Y superfamily. Addictive in the same way as Tetris. (Clustal didn't work, > for various reasons, I had to do it by hand.) And what I found was that you > get scooped if you identify a previously unrecognized domain, mutate it and > show that it is required for function, but don't know what it does! I found > 4 new conserved regions in my protein and got scooped on every one because I > didn't have the biological tools or insight to figure out what molecularly > they did. (But I did learn that my intuition is usually right and to be > aggressive about developing new techniques or using known ones to > characterize things. It taught me to be more creative in terms of > experiments and techniques.) I dabbled in covariance, but it was too close > to the end of my PhD to go anywhere... Anyway, hopefully that convinces you > I know what I'm talking about. And if it doesn't, I don't really care! > > The difference b/w regular and tiling microarrays, for non-specialists, is > that microarrays have one DNA oligo per gene so most of the DNA in a genome > is not represented, whereas tiling microarrays literally "tile" the genome > so that oligo 1 has nucleotides 1-30, oligo 2 has nucleotides 8-38, oligo 3 > has 16-46, etc. And the reverse strand is offset by 4. I don't know why > they picked that density, but you can do it with more or less overlap if you > custom design arrays. But it is $$$$$!! > > Another aside: if Ron, or any other math types, would be interested in > helping out with the statistics of tiling microarrays, we might be able to > potentially collaborate. They are still fairly prototype--I think the yeast > people have got it figured out better, but the bacterial community totally > doesn't know how to extract numerical information out of the tiling arrays > very well yet. We literally only have a graphical interface at this point > that Affymetrix provided--you literally have to scan the entire histogram of > the entire genome by eye at this point. Extremely inefficient! > > Anonymous #2 > > PS Happy Birthday, Ron > > > > >
March 16, 200817 yr I have this crazy tendency to not recognize people I know, in public. I don't understand it. Either my long term memory is shot or I need glasses, I don't know, but it makes for some pretty awkward situations when people approach me. Anyone else have this problem with facial recognition? This is becoming a serious problem lol Lay off the weed, bro. http://www.gardenscure.com/420/marijuana-cooking/52152-marijuana-capsules.html I don't smoke weed but maybe I should lay off the Natty light for a while. Hangover + riding in a car with chris= getting out and vomiting in an over-the-rhine lot on the way to your house. St. Patrick's Day, that's my excuse :drunk:
March 17, 200817 yr you cannot lose in a defamation suit if it's clear that you're giving your own personal opinion. But you can lose a defamation suit if you state something as fact in an "opinion piece". The US Supreme Court decided that when Mike Milkovich (then Maple Heights's wrestling coach) sued Ted Diaduin (then with a Lake County paper now with the PeeDee).
March 17, 200817 yr you cannot lose in a defamation suit if it's clear that you're giving your own personal opinion. But you can lose a defamation suit if you state something as fact in an "opinion piece". The US Supreme Court decided that when Mike Milkovich (then Maple Heights's wrestling coach) sued Ted Diaduin (then with a Lake County paper now with the PeeDee). I appreciate everyone's input on this. Rather than even RISK a lawsuit, I think my only two choices are to publish under a fake name or to make the book fiction and change so many details about each person's story that there's no way you could argue I was talking about a real person or a person that people could identify as someone I was with at any given time. I really don't want to do the latter.
March 17, 200817 yr E Rocc, that's why I clearly said "It has to be clear that it is your opinion". I wonder if there are publishers who are willing to take on that kind of legal risk and pay for lawyer fees (as they would potentially be held liable too, in publishing the information).
March 17, 200817 yr Opinion or no, defamation laws are designed to shift the overwhelming burden of proof on to the plaintiff, and the criteria--de facto falsehood, demonstrable harm, etc.--are nearly unprovable. In practice, it's almost impossible to win a defamation claim, but the threat of one is usually enough to make the offending defendant clam up. Result: defamation laws are a speech chiller and little else. One good thing about U.S. defamation law: corporations can't use it to single out critics. Not so the case in the UK: http://www.mcspotlight.org/case/
March 17, 200817 yr California Student Stops Out-of-Control School Bus; Gets Detention for Skipping Class Sunday , March 16, 2008 AP SEASIDE, Calif. — A 15-year-old girl who stopped an out-of-control school bus she was riding on was handed a Saturday detention instead because she was skipping school. Marina High School student Amanda Rouse was on a bus with 40 elementary school students Wednesday morning when the driver fell out of her seat after a turn and hit her head. ----I hate idiotic people. She should be rewarded for possibly saving lives. Saturday school? Blah, come on. The only problem with her "skipping" school is that she got caught. Loser school system.
March 18, 200817 yr Don't get me wrong, I have nothing against Christians but some of them really give up some dumb stuff for lent. It's usually younger people but they should know better if they're 21. This girl came over to our house tonight (to make her boyfriend jealous) and we're talking in the living room and somehow it got brought up, she asked me if I'm giving anything up and I said no, so I asked her if she is and she said she gave up CHEESE. Come to find out this girl is LACTOSE INTOLERANT. Wtf. That's such a cop-out. I don't see why people give up trivial materialistic things for a spiritual religion. I think if I had to give something up, I would give up being a sarcastic @sshole.
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